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Chronic Pyruvate Supplementation Increases Exploratory Activity and Brain Energy Reserves in Young and Middle-Aged Mice

Numerous studies have reported neuroprotective effects of pyruvate when given in systemic injections. Impaired glucose uptake and metabolism are found in Alzheimer’s disease (AD) and in AD mouse models. We tested whether dietary pyruvate supplementation is able to provide added energy supply to brai...

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Detalles Bibliográficos
Autores principales:	Koivisto, Hennariikka, Leinonen, Henri, Puurula, Mari, Hafez, Hani Sayed, Barrera, Glenda Alquicer, Stridh, Malin H., Waagepetersen, Helle S., Tiainen, Mika, Soininen, Pasi, Zilberter, Yuri, Tanila, Heikki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794631/ https://www.ncbi.nlm.nih.gov/pubmed/27014054 http://dx.doi.org/10.3389/fnagi.2016.00041

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