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Structural and functional analysis of RopB: a major virulence regulator in S treptococcus pyogenes

Group A Streptococcus (GAS) is an exclusive human pathogen that causes significant disease burden. Global regulator RopB of GAS controls the expression of several major virulence factors including secreted protease SpeB during high cell density. However, the molecular mechanism for RopB‐dependent sp...

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Detalles Bibliográficos
Autores principales: Makthal, Nishanth, Gavagan, Maire, Do, Hackwon, Olsen, Randall J., Musser, James M., Kumaraswami, Muthiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794775/
https://www.ncbi.nlm.nih.gov/pubmed/26714274
http://dx.doi.org/10.1111/mmi.13294