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Inhibition of Src homology 2 domain‐containing phosphatase 1 increases insulin sensitivity in high‐fat diet‐induced insulin‐resistant mice
Insulin resistance plays a crucial role in the development of type 2 diabetes. Insulin receptor signalling is antagonized and tightly controlled by protein tyrosine phosphatases (PTPs). However, the precise role of the PTP src homology 2 domain‐containing phosphatase 1 (SHP‐1) in insulin resistance...
Autores principales: | Krüger, Janine, Wellnhofer, Ernst, Meyborg, Heike, Stawowy, Philipp, Östman, Arne, Kintscher, Ulrich, Kappert, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794785/ https://www.ncbi.nlm.nih.gov/pubmed/27047746 http://dx.doi.org/10.1002/2211-5463.12000 |
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