mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

The branched‐chain α‐ketoacid dehydrogenase (BCKDH) complex regulates branched‐chain amino acid (BCAA) catabolism by controlling the second step of this catabolic pathway. In the present study, we examined the in vivo effects of treatment with an mTORC1 inhibitor, rapamycin, on cardiac BCKDH complex...

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Detalles Bibliográficos
Autores principales: Zhen, Hongmin, Kitaura, Yasuyuki, Kadota, Yoshihiro, Ishikawa, Takuya, Kondo, Yusuke, Xu, Minjun, Morishita, Yukako, Ota, Miki, Ito, Tomokazu, Shimomura, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794793/
https://www.ncbi.nlm.nih.gov/pubmed/27047741
http://dx.doi.org/10.1002/2211-5463.12007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794793/
https://www.ncbi.nlm.nih.gov/pubmed/27047741
http://dx.doi.org/10.1002/2211-5463.12007

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