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Quantitative thermophoretic study of disease-related protein aggregates

Amyloid fibrils are a hallmark of a range of neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. A detailed understanding of the physico-chemical properties of the different aggregated forms of proteins, and of their interactions with other compounds of diagnostic or therape...

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Detalles Bibliográficos
Autores principales: Wolff , Manuel, Mittag, Judith J., Herling, Therese W., Genst, Erwin De, Dobson, Christopher M., Knowles, Tuomas P. J., Braun, Dieter, Buell, Alexander K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794802/
https://www.ncbi.nlm.nih.gov/pubmed/26984748
http://dx.doi.org/10.1038/srep22829