Cargando…

High pneumococcal density correlates with more mucosal inflammation and reduced respiratory syncytial virus disease severity in infants

BACKGROUND: Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infections in infants. A small percentage of the infected infants develops a severe infection, while most of these severely ill patients were previously healthy. It remains unclear why these children devel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vissers, Marloes, Ahout, Inge M., van den Kieboom, Corné H., van der Gaast de Jongh, Christa E., Groh, Laszlo, Cremers, Amelieke J., de Groot, Ronald, de Jonge, Marien I., Ferwerda, Gerben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794819/ https://www.ncbi.nlm.nih.gov/pubmed/26983753 http://dx.doi.org/10.1186/s12879-016-1454-x

Ejemplares similares

Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses
por: Ederveen, Thomas H. A., et al.
Publicado: (2018)

Aptamers for respiratory syncytial virus detection
por: Percze, Krisztina, et al.
Publicado: (2017)

Phage-Derived Protein Induces Increased Platelet Activation and Is Associated with Mortality in Patients with Invasive Pneumococcal Disease
por: Tunjungputri, Rahajeng N., et al.
Publicado: (2017)

Siglec‐1 inhibits RSV‐induced interferon gamma production by adult T cells in contrast to newborn T cells
por: Jans, Jop, et al.
Publicado: (2018)

Differential Pneumococcal Growth Features in Severe Invasive Disease Manifestations
por: Arends, Daan W., et al.
Publicado: (2022)

Elucidation and Clinical Role of Emerging Viral Respiratory Tract Infections in Children
por: de Groot, Ronald, et al.
Publicado: (2012)

A novel flow cytometry-based assay for the quantification of antibody-dependent pneumococcal agglutination
por: Habets, Marrit N., et al.
Publicado: (2017)

Aptasensors for viral diagnostics
por: van den Kieboom, Corné H., et al.
Publicado: (2015)

Actin- and clathrin-dependent mechanisms regulate interferon gamma release after stimulation of human immune cells with respiratory syncytial virus
por: Jans, Jop, et al.
Publicado: (2016)

The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition
por: Cremers, Amelieke JH, et al.
Publicado: (2014)

Short-term repeated HRV-16 exposure results in an attenuated immune response in vivo in humans
por: Koch, Rebecca M., et al.
Publicado: (2018)

In Vitro Enhancement of Respiratory Syncytial Virus Infection by Maternal Antibodies Does Not Explain Disease Severity in Infants
por: van Erp, Elisabeth A., et al.
Publicado: (2017)

Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age
por: Jans, Jop, et al.
Publicado: (2017)

Transcriptome assists prognosis of disease severity in respiratory syncytial virus infected infants
por: Jong, Victor L., et al.
Publicado: (2016)

Direct multiplexed whole genome sequencing of respiratory tract samples reveals full viral genomic information
por: Zoll, Jan, et al.
Publicado: (2015)

The post-vaccine microevolution of invasive Streptococcus pneumoniae
por: Cremers, Amelieke J. H., et al.
Publicado: (2015)

Impact of Experimental Human Pneumococcal Carriage on Nasopharyngeal Bacterial Densities in Healthy Adults
por: Shak, Joshua R., et al.
Publicado: (2014)

Natural killer cell activation by respiratory syncytial virus‐specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc‐glycosylation
por: van Erp, Elisabeth A, et al.
Publicado: (2020)

Broad range detection of viral and bacterial pathogens in bronchoalveolar lavage fluid of children to identify the cause of lower respiratory tract infections
por: Wang, Heping, et al.
Publicado: (2021)

Prospective observational study in two Dutch hospitals to assess the performance of inflammatory plasma markers to determine disease severity of viral respiratory tract infections in children
por: Ahout, Inge M L, et al.
Publicado: (2017)

Deciphering the distance to antibiotic resistance for the pneumococcus using genome sequencing data
por: Mobegi, Fredrick M., et al.
Publicado: (2017)

Assessment of a molecular diagnostic platform for integrated isolation and quantification of mRNA in whole blood
por: van den Kieboom, C. H., et al.
Publicado: (2015)

Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) Infection
por: Brand, H. K., et al.
Publicado: (2015)

Fc-Mediated Antibody Effector Functions During Respiratory Syncytial Virus Infection and Disease
por: van Erp, Elisabeth A., et al.
Publicado: (2019)

Nasopharyngeal colonisation dynamics of bacterial pathogens in patients with fever in rural Burkina Faso: an observational study
por: Martens, Liesbeth, et al.
Publicado: (2022)

Lack of Cell Cycle Inhibitor p21 and Low CD4(+) T Cell Suppression in Newborns After Exposure to IFN-β
por: Jans, Jop, et al.
Publicado: (2021)

SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
por: Fröberg, Janeri, et al.
Publicado: (2021)

Detection and serotyping of pneumococci in community acquired pneumonia patients without culture using blood and urine samples
por: Elberse, Karin, et al.
Publicado: (2015)

Pathogenesis of Respiratory Syncytial Virus Infection in BALB/c Mice Differs Between Intratracheal and Intranasal Inoculation
por: van Erp, Elisabeth A., et al.
Publicado: (2019)

From microbial gene essentiality to novel antimicrobial drug targets
por: Mobegi, Fredrick M, et al.
Publicado: (2014)

Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice
por: van der Maten, Erika, et al.
Publicado: (2016)

Genome-Wide Identification of Genes Essential for the Survival of Streptococcus pneumoniae in Human Saliva
por: Verhagen, Lilly M., et al.
Publicado: (2014)

Density and duration of experimental human pneumococcal carriage
por: Gritzfeld, J F, et al.
Publicado: (2014)

Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice
por: Fransen, Floris, et al.
Publicado: (2017)

The Impact of Gut Microbiota on Gender-Specific Differences in Immunity
por: Fransen, Floris, et al.
Publicado: (2017)

Lipidation of Pneumococcal Antigens Leads to Improved Immunogenicity and Protection
por: Voß, Franziska, et al.
Publicado: (2020)

Respiratory Syncytial Virus Infects Primary Neonatal and Adult Natural Killer Cells and Affects Their Antiviral Effector Function
por: van Erp, Elisabeth A, et al.
Publicado: (2019)

Pneumococcal colonization and invasive disease studied in a porcine model
por: de Greeff, Astrid, et al.
Publicado: (2016)

Timing and sequence of vaccination against COVID-19 and influenza – Author's reply
por: Dulfer, Elisabeth A., et al.
Publicado: (2023)

The drop in reported invasive pneumococcal disease among adults during the first COVID-19 wave in the Netherlands explained.
por: Dirkx, Kirsten K.T., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2dvspn0nsk5ebbuhldnbhu3s8t