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Identification of Plasmodium falciparum specific translation inhibitors from the MMV Malaria Box using a high throughput in vitro translation screen
BACKGROUND: A major goal in the search for new anti-malarial compounds is to identify new mechanisms of action or new molecular targets. While cell-based, growth inhibition-based screening have enjoyed tremendous success, an alternative approach is to specifically assay a given pathway or essential...
Autores principales: | Ahyong, Vida, Sheridan, Christine M., Leon, Kristoffer E., Witchley, Jessica N., Diep, Jonathan, DeRisi, Joseph L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794828/ https://www.ncbi.nlm.nih.gov/pubmed/26987601 http://dx.doi.org/10.1186/s12936-016-1231-8 |
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