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Nuclear expression of Lyn, a Src family kinase member, is associated with poor prognosis in renal cancer patients
BACKGROUND: 8000 cases of renal cancer are diagnosed each year in the UK, with a five-year survival rate of 50 %. Treatment options are limited; a potential therapeutic target is the Src family kinases (SFKs). SFKs have roles in multiple oncogenic processes and promote metastases in solid tumours. T...
Autores principales: | Roseweir, Antonia K., Qayyum, Tahir, Lim, Zhi, Hammond, Rachel, MacDonald, Alasdair I., Fraser, Sioban, Oades, Grenville M., Aitchison, Michael, Jones, Robert J., Edwards, Joanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794832/ https://www.ncbi.nlm.nih.gov/pubmed/26984511 http://dx.doi.org/10.1186/s12885-016-2254-9 |
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