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The transcription factor scleraxis is a critical regulator of cardiac fibroblast phenotype
BACKGROUND: Resident fibroblasts synthesize the cardiac extracellular matrix, and can undergo phenotype conversion to myofibroblasts to augment matrix production, impairing function and contributing to organ failure. A significant gap in our understanding of the transcriptional regulation of these p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794909/ https://www.ncbi.nlm.nih.gov/pubmed/26988708 http://dx.doi.org/10.1186/s12915-016-0243-8 |