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Use of the non-radioactive SUnSET method to detect decreased protein synthesis in proteasome inhibited Arabidopsis roots

BACKGROUND: In eukaryotic cells, the proteasome maintains homeostasis by selectively degrading regulatory and misfolded proteins, and in doing so contributes to the amino acid pool. Inhibition of the proteasome in yeast and human cells decreases de novo protein synthesis. However, it is not know if...

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Detalles Bibliográficos
Autor principal: Van Hoewyk, Doug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794914/
https://www.ncbi.nlm.nih.gov/pubmed/26989430
http://dx.doi.org/10.1186/s13007-016-0120-z