A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses

BACKGROUND: NF-κB is widely involved in lymphoid malignancies; however, the functional roles and specific transcriptomes of NF-κB dimers with distinct subunit compositions have been unclear. METHODS: Using combined ChIP-sequencing and microarray analyses, we determined the cistromes and target gene...

Descripción completa

Detalles Bibliográficos
Autores principales: de Oliveira, Kivia A. P., Kaergel, Eva, Heinig, Matthias, Fontaine, Jean-Fred, Patone, Giannino, Muro, Enrique M., Mathas, Stephan, Hummel, Michael, Andrade-Navarro, Miguel A., Hübner, Norbert, Scheidereit, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794921/
https://www.ncbi.nlm.nih.gov/pubmed/26988706
http://dx.doi.org/10.1186/s13073-016-0280-5

Ejemplares similares

Ejemplares similares