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Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient

Prone position ventilation (PPV) improves mortality in severe acute respiratory distress syndrome (ARDS), but outcomes following its use in lung transplant recipients are not known. We report the case of a 42-year-old Caucasian man who presented with severe ARDS from Bordetella pertussis, 5 years af...

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Autores principales: Panchabhai, Tanmay S, Bandyopadhyay, Debabrata, Kapoor, Aanchal, Akindipe, Olufemi, Lane, Charles, Krishnan, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795362/
https://www.ncbi.nlm.nih.gov/pubmed/27051622
http://dx.doi.org/10.4103/2229-5151.177367
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author Panchabhai, Tanmay S
Bandyopadhyay, Debabrata
Kapoor, Aanchal
Akindipe, Olufemi
Lane, Charles
Krishnan, Sudhir
author_facet Panchabhai, Tanmay S
Bandyopadhyay, Debabrata
Kapoor, Aanchal
Akindipe, Olufemi
Lane, Charles
Krishnan, Sudhir
author_sort Panchabhai, Tanmay S
collection PubMed
description Prone position ventilation (PPV) improves mortality in severe acute respiratory distress syndrome (ARDS), but outcomes following its use in lung transplant recipients are not known. We report the case of a 42-year-old Caucasian man who presented with severe ARDS from Bordetella pertussis, 5 years after bilateral sequential lung transplant for cystic fibrosis. He was managed with PPV for 22 days and had a prolonged ICU stay complicated by hypoxic ischemic optic neuropathy leading to blindness. Since his discharge from the ICU 6 months ago, his FEV(1) has recovered to 47% predicted compared to his pre-ICU peak FEV(1) of 85% predicted, suggesting recovery of lung function. This is the first report of optic nerve damage and vision loss in patients undergoing PPV. Our report also suggests that, in appropriately selected lung transplant recipients, severe hypoxemia could potentially be managed with prone ventilation.
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spelling pubmed-47953622016-04-05 Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient Panchabhai, Tanmay S Bandyopadhyay, Debabrata Kapoor, Aanchal Akindipe, Olufemi Lane, Charles Krishnan, Sudhir Int J Crit Illn Inj Sci Case Report Prone position ventilation (PPV) improves mortality in severe acute respiratory distress syndrome (ARDS), but outcomes following its use in lung transplant recipients are not known. We report the case of a 42-year-old Caucasian man who presented with severe ARDS from Bordetella pertussis, 5 years after bilateral sequential lung transplant for cystic fibrosis. He was managed with PPV for 22 days and had a prolonged ICU stay complicated by hypoxic ischemic optic neuropathy leading to blindness. Since his discharge from the ICU 6 months ago, his FEV(1) has recovered to 47% predicted compared to his pre-ICU peak FEV(1) of 85% predicted, suggesting recovery of lung function. This is the first report of optic nerve damage and vision loss in patients undergoing PPV. Our report also suggests that, in appropriately selected lung transplant recipients, severe hypoxemia could potentially be managed with prone ventilation. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4795362/ /pubmed/27051622 http://dx.doi.org/10.4103/2229-5151.177367 Text en Copyright: © 2016 International Journal of Critical Illness and Injury Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Panchabhai, Tanmay S
Bandyopadhyay, Debabrata
Kapoor, Aanchal
Akindipe, Olufemi
Lane, Charles
Krishnan, Sudhir
Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
title Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
title_full Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
title_fullStr Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
title_full_unstemmed Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
title_short Acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
title_sort acute ischemic optic neuropathy with extended prone position ventilation in a lung transplant recipient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795362/
https://www.ncbi.nlm.nih.gov/pubmed/27051622
http://dx.doi.org/10.4103/2229-5151.177367
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