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Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect

Delivering radiotherapy to the postmastectomy chest wall can be achieved using matched electron fields. Surgical defects of the chest wall change the dose distribution of electrons. In this study, the improvement of dose homogeneity using simple, nonconformal techniques of thermoplastic bolus applic...

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Autores principales: Mahdavi, Hoda, Jabbari, Keyvan, Roayaei, Mahnaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795416/
https://www.ncbi.nlm.nih.gov/pubmed/27051169
http://dx.doi.org/10.4103/0971-6203.177288
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author Mahdavi, Hoda
Jabbari, Keyvan
Roayaei, Mahnaz
author_facet Mahdavi, Hoda
Jabbari, Keyvan
Roayaei, Mahnaz
author_sort Mahdavi, Hoda
collection PubMed
description Delivering radiotherapy to the postmastectomy chest wall can be achieved using matched electron fields. Surgical defects of the chest wall change the dose distribution of electrons. In this study, the improvement of dose homogeneity using simple, nonconformal techniques of thermoplastic bolus application on a defect is evaluated. The proposed phantom design improves the capability of film dosimetry for obtaining dose profiles of a patient's anatomical condition. A modeled electron field of a patient with a postmastectomy inward surgical defect was planned. High energy electrons were delivered to the phantom in various settings, including no bolus, a bolus that filled the inward defect (PB0), a uniform thickness bolus of 5 mm (PB1), and two 5 mm boluses (PB2). A reduction of mean doses at the base of the defect was observed by any bolus application. PB0 increased the dose at central parts of the defect, reduced hot areas at the base of steep edges, and reduced dose to the lung and heart. Thermoplastic boluses that compensate a defect (PB0) increased the homogeneity of dose in a fixed depth from the surface; adversely, PB2 increased the dose heterogeneity. This study shows that it is practical to investigate dose homogeneity profiles inside a target volume for various techniques of electron therapy.
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spelling pubmed-47954162016-04-05 Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect Mahdavi, Hoda Jabbari, Keyvan Roayaei, Mahnaz J Med Phys Original Article Delivering radiotherapy to the postmastectomy chest wall can be achieved using matched electron fields. Surgical defects of the chest wall change the dose distribution of electrons. In this study, the improvement of dose homogeneity using simple, nonconformal techniques of thermoplastic bolus application on a defect is evaluated. The proposed phantom design improves the capability of film dosimetry for obtaining dose profiles of a patient's anatomical condition. A modeled electron field of a patient with a postmastectomy inward surgical defect was planned. High energy electrons were delivered to the phantom in various settings, including no bolus, a bolus that filled the inward defect (PB0), a uniform thickness bolus of 5 mm (PB1), and two 5 mm boluses (PB2). A reduction of mean doses at the base of the defect was observed by any bolus application. PB0 increased the dose at central parts of the defect, reduced hot areas at the base of steep edges, and reduced dose to the lung and heart. Thermoplastic boluses that compensate a defect (PB0) increased the homogeneity of dose in a fixed depth from the surface; adversely, PB2 increased the dose heterogeneity. This study shows that it is practical to investigate dose homogeneity profiles inside a target volume for various techniques of electron therapy. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4795416/ /pubmed/27051169 http://dx.doi.org/10.4103/0971-6203.177288 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mahdavi, Hoda
Jabbari, Keyvan
Roayaei, Mahnaz
Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
title Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
title_full Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
title_fullStr Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
title_full_unstemmed Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
title_short Evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
title_sort evaluation of various boluses in dose distribution for electron therapy of the chest wall with an inward defect
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795416/
https://www.ncbi.nlm.nih.gov/pubmed/27051169
http://dx.doi.org/10.4103/0971-6203.177288
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