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Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells

Tocopherylquinone (TQ), the oxidation product of alpha-tocopherol (AT), is a bioactive molecule with distinct properties from AT. In this study, AT and TQ are investigated for their comparative effects on growth and androgenic activity in prostate cancer cells. TQ potently inhibited the growth of an...

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Detalles Bibliográficos
Autores principales: Fajardo, Alexandra M., MacKenzie, Debra A., Olguin, Sarah L., Scariano, John K., Rabinowitz, Ian, Thompson, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795544/
https://www.ncbi.nlm.nih.gov/pubmed/26986969
http://dx.doi.org/10.1371/journal.pone.0151525