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Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells
Tocopherylquinone (TQ), the oxidation product of alpha-tocopherol (AT), is a bioactive molecule with distinct properties from AT. In this study, AT and TQ are investigated for their comparative effects on growth and androgenic activity in prostate cancer cells. TQ potently inhibited the growth of an...
Autores principales: | Fajardo, Alexandra M., MacKenzie, Debra A., Olguin, Sarah L., Scariano, John K., Rabinowitz, Ian, Thompson, Todd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795544/ https://www.ncbi.nlm.nih.gov/pubmed/26986969 http://dx.doi.org/10.1371/journal.pone.0151525 |
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