Cargando…

Toward antituberculosis drugs: in silico screening of synthetic compounds against Mycobacterium tuberculosis l,d-transpeptidase 2

Mycobacterium tuberculosis (Mtb) the main causative agent of tuberculosis, is the main reason why this disease continues to be a global public health threat. It is therefore imperative to find a novel antitubercular drug target that is unique to the structural machinery or is essential to the growth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Billones, Junie B, Carrillo, Maria Constancia O, Organo, Voltaire G, Macalino, Stephani Joy Y, Sy, Jamie Bernadette A, Emnacen, Inno A, Clavio, Nina Abigail B, Concepcion, Gisela P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795573/ https://www.ncbi.nlm.nih.gov/pubmed/27042006 http://dx.doi.org/10.2147/DDDT.S97043

Ejemplares similares

In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase (Mtb BioA)
por: Billones, Junie B, et al.
Publicado: (2017)

In Silico Strategies in Tuberculosis Drug Discovery
por: Macalino, Stephani Joy Y., et al.
Publicado: (2020)

Synthesis and crystal structure of [2,7,12-trimethyl-3,7,11,17-tetraazabicyclo[11.3.1]heptadeca-1(17),13,15-triene-κ(4) N]copper(II) bis(perchlorate)
por: Hilvano, Edward Gabrielle V., et al.
Publicado: (2016)

In silico evaluation of Philippine Natural Products against SARS-CoV-2 Main Protease
por: Cheng, Adrian Josiah T., et al.
Publicado: (2022)

Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery
por: Macalino, Stephani Joy Y., et al.
Publicado: (2018)

In Ovo and In Silico Evaluation of the Anti-Angiogenic Potential of Syringin
por: Aventurado, Charlaine A, et al.
Publicado: (2020)

Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design
por: Basith, Shaherin, et al.
Publicado: (2018)

In silico study of phytochemicals contained in Brucea javanica in inhibiting the InhA enzyme as antituberculosis
por: Sulistyowaty, Melanny Ika, et al.
Publicado: (2023)

Gamma-glutamyl transpeptidase to platelet and gamma-glutamyl transpeptidase to lymphocyte ratio in a sample of Chinese Han population
por: Chen, Weijie, et al.
Publicado: (2022)

Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics
por: Biecker, Ashley L., et al.
Publicado: (2019)

An Electrochemical Method to Detect Gamma Glutamyl Transpeptidase
por: Chen, Guifang, et al.
Publicado: (2012)

Acquired Resistance to Antituberculosis Drugs
por: Aung, Htin Lin, et al.
Publicado: (2018)

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations
por: Pinto, Vinícius de S., et al.
Publicado: (2019)

Non-classical transpeptidases yield insight into new antibacterials
por: Kumar, Pankaj, et al.
Publicado: (2016)

The clinical implication of gamma-glutamyl transpeptidase in COVID-19()
por: Liu, Jianrong, et al.
Publicado: (2021)

Antituberculosis drug-induced hepatotoxicity in children
por: Donald, Peter R
Publicado: (2011)

Population Pharmacokinetics of the Antituberculosis Agent Pretomanid
por: Salinger, David H., et al.
Publicado: (2019)

Diagnosis of Hypersensitivity Induced by Antituberculosis Drugs
por: Wu, Yuqing, et al.
Publicado: (2021)

Roles of Virtual Screening and Molecular Dynamics Simulations in Discovering and Understanding Antimalarial Drugs
por: Duay, Searle S., et al.
Publicado: (2023)

Diabetic and non-diabetic human cornea and tear γ-glutamyl transpeptidase activity
por: Burnham, Jordan M, et al.
Publicado: (2013)

Is gamma-glutamyl transpeptidase a biomarker for oxidative stress in periodontitis?
por: Sreeram, Meenakshi, et al.
Publicado: (2015)

Mycobacterium tuberculosis resistance to antituberculosis drugs in Mozambique,
por: Pires, Germano Manuel, et al.
Publicado: (2014)

The impact of immune disturbances on the failure of antituberculosis treatment
por: LESNIC, EVELINA, et al.
Publicado: (2016)

Empyema Necessitans due to Interruption of Antituberculosis Treatment
por: Benaragama, H. N., et al.
Publicado: (2019)

In silico identification of novel chemical compounds with antituberculosis activity for the inhibition of InhA and EthR proteins from Mycobacterium tuberculosis
por: Halder, Sajal Kumar, et al.
Publicado: (2021)

Investigating the Antituberculosis Activity of Selected Commercial Essential Oils and Identification of Active Constituents Using a Biochemometrics Approach and In Silico Modeling
por: Boussamba-Digombou, Katyna J., et al.
Publicado: (2022)

Serum levels of gamma-glutamyl transpeptidase in relation to HCC human biology and prognosis
por: Carr, BI, et al.
Publicado: (2020)

Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
por: Pereira, M A, et al.
Publicado: (1983)

Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction
por: Qiao, Yuan, et al.
Publicado: (2014)

Structural and biochemical analyses of a Clostridium perfringens sortase D transpeptidase
por: Suryadinata, Randy, et al.
Publicado: (2015)

Drinking Amount Associated with Abnormal Gamma-Glutamyl Transpeptidase Expression in Women
por: Yang, Jun-Seok, et al.
Publicado: (2016)

Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials
por: Sauvage, Eric, et al.
Publicado: (2016)

Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin
por: Yoshimoto, Naoko, et al.
Publicado: (2015)

Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus
por: Maya-Martinez, Roberto, et al.
Publicado: (2019)

Allosteric cooperation in β-lactam binding to a non-classical transpeptidase
por: Ahmad, Nazia, et al.
Publicado: (2022)

Kinetic Features of L,D-Transpeptidase Inactivation Critical for β-Lactam Antibacterial Activity
por: Triboulet, Sébastien, et al.
Publicado: (2013)

Mycobacterium tuberculosis Specific CD8(+) T Cells Rapidly Decline with Antituberculosis Treatment
por: Nyendak, Melissa R., et al.
Publicado: (2013)

The Effect of an Antituberculosis Serum on the Development of Experimental Tuberculosis of the Skin
por: Thomas, Robert M., et al.
Publicado: (1940)

Barriers to Initiation of Antiretrovirals during Antituberculosis Therapy in Africa
por: Pepper, Dominique J., et al.
Publicado: (2011)

The Chemical Components of Sesbania grandiflora Root and Their Antituberculosis Activity
por: Hasan, Noviany, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ormrf005amstp66b6era5eeehg