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In Situ Staining and Laser Capture Microdissection of Lymph Node Residing SIV Gag-Specific CD8(+) T cells—A Tool to Interrogate a Functional Immune Response Ex Vivo
While a plethora of data describes the essential role of systemic CD8(+) T cells in the control of SIV replication little is known about the local in situ CD8(+) T cell immune responses against SIV at the intact tissue level, due to technical limitations. In situ staining, using GagCM9 Qdot 655 mult...
Autores principales: | Tjernlund, Annelie, Burgener, Adam, Lindvall, Jessica M., Peng, Tao, Zhu, Jia, Öhrmalm, Lars, Picker, Louis J., Broliden, Kristina, McElrath, M. Juliana, Corey, Lawrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795610/ https://www.ncbi.nlm.nih.gov/pubmed/26986062 http://dx.doi.org/10.1371/journal.pone.0149907 |
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