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Subtle balance of tropoelastin molecular shape and flexibility regulates dynamics and hierarchical assembly

The assembly of the tropoelastin monomer into elastin is vital for conferring elasticity on blood vessels, skin, and lungs. Tropoelastin has dual needs for flexibility and structure in self-assembly. We explore the structure-dynamics-function interplay, consider the duality of molecular order and di...

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Detalles Bibliográficos
Autores principales: Yeo, Giselle C., Tarakanova, Anna, Baldock, Clair, Wise, Steven G., Buehler, Markus J., Weiss, Anthony S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795673/
https://www.ncbi.nlm.nih.gov/pubmed/26998516
http://dx.doi.org/10.1126/sciadv.1501145