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Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G
Protease-mediated degradation of proteins is critical in a plethora of physiological processes. Neutrophils secrete serine proteases including cathepsin G (CatG), neutrophile elastase (NE), and proteinase 3 (PR3) together with lactoferrin (LF) as a first cellular immune response against pathogens. H...
Autores principales: | Eipper, Steffen, Steiner, Robin, Lesner, Adam, Sienczyk, Marcin, Palesch, David, Halatsch, Marc-Eric, Zaczynska, Ewa, Heim, Christopher, Hartmann, Marcus D., Zimecki, Michal, Wirtz, Christian Rainer, Burster, Timo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795699/ https://www.ncbi.nlm.nih.gov/pubmed/26986619 http://dx.doi.org/10.1371/journal.pone.0151509 |
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