Using Sex to Cure the Genome

The diversification of prokaryotes is accelerated by their ability to acquire DNA from other genomes. However, the underlying processes also facilitate genome infection by costly mobile genetic elements. The discovery that cells can uptake DNA by natural transformation was instrumental to the birth...

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Detalles Bibliográficos
Autor principal: Rocha, Eduardo P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795794/
https://www.ncbi.nlm.nih.gov/pubmed/26987049
http://dx.doi.org/10.1371/journal.pbio.1002417
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author Rocha, Eduardo P. C.
author_facet Rocha, Eduardo P. C.
author_sort Rocha, Eduardo P. C.
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description The diversification of prokaryotes is accelerated by their ability to acquire DNA from other genomes. However, the underlying processes also facilitate genome infection by costly mobile genetic elements. The discovery that cells can uptake DNA by natural transformation was instrumental to the birth of molecular biology nearly a century ago. Surprisingly, a new study shows that this mechanism could efficiently cure the genome of mobile elements acquired through previous sexual exchanges.
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spelling pubmed-47957942016-03-23 Using Sex to Cure the Genome Rocha, Eduardo P. C. PLoS Biol Primer The diversification of prokaryotes is accelerated by their ability to acquire DNA from other genomes. However, the underlying processes also facilitate genome infection by costly mobile genetic elements. The discovery that cells can uptake DNA by natural transformation was instrumental to the birth of molecular biology nearly a century ago. Surprisingly, a new study shows that this mechanism could efficiently cure the genome of mobile elements acquired through previous sexual exchanges. Public Library of Science 2016-03-17 /pmc/articles/PMC4795794/ /pubmed/26987049 http://dx.doi.org/10.1371/journal.pbio.1002417 Text en © 2016 Eduardo P. C. Rocha http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Primer
Rocha, Eduardo P. C.
Using Sex to Cure the Genome
title Using Sex to Cure the Genome
title_full Using Sex to Cure the Genome
title_fullStr Using Sex to Cure the Genome
title_full_unstemmed Using Sex to Cure the Genome
title_short Using Sex to Cure the Genome
title_sort using sex to cure the genome
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795794/
https://www.ncbi.nlm.nih.gov/pubmed/26987049
http://dx.doi.org/10.1371/journal.pbio.1002417
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