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Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Allevi-ating Endoplasmic Reticulum Stress in Rats
Acute kidney injury (AKI) is one of the most severe complications of rhabdomyolysis (RM). The underlying mechanisms and potential preventions need to be investigated. Penehyclidine hydrochloride (PHC) was reported to ameliorate renal ischemia-reperfusion injury, but the effect of PHC on RM-reduced A...
Autores principales: | Zhao, Wei, Huang, XuDong, Zhang, LiXia, Yang, XinJun, Wang, LiHui, Chen, YunShuang, Wang, JingHua, Wu, GuangLi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795801/ https://www.ncbi.nlm.nih.gov/pubmed/26987113 http://dx.doi.org/10.1371/journal.pone.0151158 |
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