Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles

Dropped head syndrome (DHS) is a famous but unusual late complication of multimodality treatment for head and neck carcinoma. We reported this early-onset complication and analyzed the dose to the neck extensor muscles. We examined the records of three patients with DHS after radiotherapy. The doses...

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Autores principales: Inaba, Koji, Nakamura, Satoshi, Okamoto, Hiroyuki, Kashihara, Tairo, Kobayashi, Kazuma, Harada, Ken, Kitaguchi, Mayuka, Sekii, Shuhei, Takahashi, Kana, Murakami, Naoya, Ito, Yoshinori, Igaki, Hiroshi, Uno, Takashi, Itami, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Clinical Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795943/
https://www.ncbi.nlm.nih.gov/pubmed/26684338
http://dx.doi.org/10.1093/jrr/rrv055
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author Inaba, Koji
Nakamura, Satoshi
Okamoto, Hiroyuki
Kashihara, Tairo
Kobayashi, Kazuma
Harada, Ken
Kitaguchi, Mayuka
Sekii, Shuhei
Takahashi, Kana
Murakami, Naoya
Ito, Yoshinori
Igaki, Hiroshi
Uno, Takashi
Itami, Jun
author_facet Inaba, Koji
Nakamura, Satoshi
Okamoto, Hiroyuki
Kashihara, Tairo
Kobayashi, Kazuma
Harada, Ken
Kitaguchi, Mayuka
Sekii, Shuhei
Takahashi, Kana
Murakami, Naoya
Ito, Yoshinori
Igaki, Hiroshi
Uno, Takashi
Itami, Jun
author_sort Inaba, Koji
collection PubMed
description Dropped head syndrome (DHS) is a famous but unusual late complication of multimodality treatment for head and neck carcinoma. We reported this early-onset complication and analyzed the dose to the neck extensor muscles. We examined the records of three patients with DHS after radiotherapy. The doses to the neck extensor muscles were compared between three patients with DHS and nine patients without DHS. The mean dose to the neck extensor muscles of the three patients with DHS were 58.5 Gy, 42.3 Gy and 60.9 Gy, while the dose was <50 Gy in all nine patients in the control group. The onset of this syndrome was 5 months, 6 months and 15 months. The early-onset DHS may have something to do with dose to the neck extensor muscles. The proposed dose to the neck extensor muscles might be <46 Gy (or at least <50 Gy).
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spelling pubmed-47959432016-03-21 Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles Inaba, Koji Nakamura, Satoshi Okamoto, Hiroyuki Kashihara, Tairo Kobayashi, Kazuma Harada, Ken Kitaguchi, Mayuka Sekii, Shuhei Takahashi, Kana Murakami, Naoya Ito, Yoshinori Igaki, Hiroshi Uno, Takashi Itami, Jun J Radiat Res Clinical Radiation Oncology Dropped head syndrome (DHS) is a famous but unusual late complication of multimodality treatment for head and neck carcinoma. We reported this early-onset complication and analyzed the dose to the neck extensor muscles. We examined the records of three patients with DHS after radiotherapy. The doses to the neck extensor muscles were compared between three patients with DHS and nine patients without DHS. The mean dose to the neck extensor muscles of the three patients with DHS were 58.5 Gy, 42.3 Gy and 60.9 Gy, while the dose was <50 Gy in all nine patients in the control group. The onset of this syndrome was 5 months, 6 months and 15 months. The early-onset DHS may have something to do with dose to the neck extensor muscles. The proposed dose to the neck extensor muscles might be <46 Gy (or at least <50 Gy). Oxford University Press 2016-03 2015-12-18 /pmc/articles/PMC4795943/ /pubmed/26684338 http://dx.doi.org/10.1093/jrr/rrv055 Text en © The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Clinical Radiation Oncology
Inaba, Koji
Nakamura, Satoshi
Okamoto, Hiroyuki
Kashihara, Tairo
Kobayashi, Kazuma
Harada, Ken
Kitaguchi, Mayuka
Sekii, Shuhei
Takahashi, Kana
Murakami, Naoya
Ito, Yoshinori
Igaki, Hiroshi
Uno, Takashi
Itami, Jun
Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
title Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
title_full Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
title_fullStr Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
title_full_unstemmed Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
title_short Early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
title_sort early-onset dropped head syndrome after radiotherapy for head and neck cancer: dose constraints for neck extensor muscles
topic Clinical Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795943/
https://www.ncbi.nlm.nih.gov/pubmed/26684338
http://dx.doi.org/10.1093/jrr/rrv055
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