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The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity

In this functional magnetic resonance imaging (fMRI) study, we evaluated the effect of self-relevance on cerebral activity and behavioral performance during an incidental encoding task. Recent findings suggest that pleasantness judgments reliably induce self-oriented (internal) thoughts and increase...

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Autores principales: Perrone-Bertolotti, Marcela, Cerles, Melanie, Ramdeen, Kylee T., Boudiaf, Naila, Pichat, Cedric, Hot, Pascal, Baciu, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796013/
https://www.ncbi.nlm.nih.gov/pubmed/27047364
http://dx.doi.org/10.3389/fnhum.2016.00121
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author Perrone-Bertolotti, Marcela
Cerles, Melanie
Ramdeen, Kylee T.
Boudiaf, Naila
Pichat, Cedric
Hot, Pascal
Baciu, Monica
author_facet Perrone-Bertolotti, Marcela
Cerles, Melanie
Ramdeen, Kylee T.
Boudiaf, Naila
Pichat, Cedric
Hot, Pascal
Baciu, Monica
author_sort Perrone-Bertolotti, Marcela
collection PubMed
description In this functional magnetic resonance imaging (fMRI) study, we evaluated the effect of self-relevance on cerebral activity and behavioral performance during an incidental encoding task. Recent findings suggest that pleasantness judgments reliably induce self-oriented (internal) thoughts and increase default mode network (DMN) activity. We hypothesized that this increase in DMN activity would relate to increased memory recognition for pleasantly-judged stimuli (which depend on internally-oriented attention) but decreased recognition for unpleasantly-judged items (which depend on externally-oriented attention). To test this hypothesis, brain activity was recorded from 21 healthy participants while they performed a pleasantness judgment requiring them to rate visual stimuli as pleasant or unpleasant. One hour later, participants performed a surprise memory recognition test outside of the scanner. Thus, we were able to evaluate the effects of pleasant and unpleasant judgments on cerebral activity and incidental encoding. The behavioral results showed that memory recognition was better for items rated as pleasant than items rated as unpleasant. The whole brain analysis indicated that successful encoding (SE) activates the inferior frontal and lateral temporal cortices, whereas unsuccessful encoding (UE) recruits two key medial posterior DMN regions, the posterior cingulate cortex (PCC) and precuneus (PCU). A region of interest (ROI) analysis including classic DMN areas, revealed significantly greater involvement of the medial prefrontal cortex (mPFC) in pleasant compared to unpleasant judgments, suggesting this region’s involvement in self-referential (i.e., internal) processing. This area may be responsible for the greater recognition performance seen for pleasant stimuli. Furthermore, a significant interaction between the encoding performance (successful vs. unsuccessful) and pleasantness was observed for the PCC, PCU and inferior frontal gyrus (IFG). Overall, our results suggest the involvement of medial frontal and parietal DMN regions during the evaluation of self-referential pleasantness. We discuss these results in terms of the introspective referential of pleasantness judgments and the differential brain modulation based on internally- vs. externally-oriented attention during encoding.
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spelling pubmed-47960132016-04-04 The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity Perrone-Bertolotti, Marcela Cerles, Melanie Ramdeen, Kylee T. Boudiaf, Naila Pichat, Cedric Hot, Pascal Baciu, Monica Front Hum Neurosci Neuroscience In this functional magnetic resonance imaging (fMRI) study, we evaluated the effect of self-relevance on cerebral activity and behavioral performance during an incidental encoding task. Recent findings suggest that pleasantness judgments reliably induce self-oriented (internal) thoughts and increase default mode network (DMN) activity. We hypothesized that this increase in DMN activity would relate to increased memory recognition for pleasantly-judged stimuli (which depend on internally-oriented attention) but decreased recognition for unpleasantly-judged items (which depend on externally-oriented attention). To test this hypothesis, brain activity was recorded from 21 healthy participants while they performed a pleasantness judgment requiring them to rate visual stimuli as pleasant or unpleasant. One hour later, participants performed a surprise memory recognition test outside of the scanner. Thus, we were able to evaluate the effects of pleasant and unpleasant judgments on cerebral activity and incidental encoding. The behavioral results showed that memory recognition was better for items rated as pleasant than items rated as unpleasant. The whole brain analysis indicated that successful encoding (SE) activates the inferior frontal and lateral temporal cortices, whereas unsuccessful encoding (UE) recruits two key medial posterior DMN regions, the posterior cingulate cortex (PCC) and precuneus (PCU). A region of interest (ROI) analysis including classic DMN areas, revealed significantly greater involvement of the medial prefrontal cortex (mPFC) in pleasant compared to unpleasant judgments, suggesting this region’s involvement in self-referential (i.e., internal) processing. This area may be responsible for the greater recognition performance seen for pleasant stimuli. Furthermore, a significant interaction between the encoding performance (successful vs. unsuccessful) and pleasantness was observed for the PCC, PCU and inferior frontal gyrus (IFG). Overall, our results suggest the involvement of medial frontal and parietal DMN regions during the evaluation of self-referential pleasantness. We discuss these results in terms of the introspective referential of pleasantness judgments and the differential brain modulation based on internally- vs. externally-oriented attention during encoding. Frontiers Media S.A. 2016-03-18 /pmc/articles/PMC4796013/ /pubmed/27047364 http://dx.doi.org/10.3389/fnhum.2016.00121 Text en Copyright © 2016 Perrone-Bertolotti, Cerles, Ramdeen, Boudiaf, Pichat, Hot and Baciu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Perrone-Bertolotti, Marcela
Cerles, Melanie
Ramdeen, Kylee T.
Boudiaf, Naila
Pichat, Cedric
Hot, Pascal
Baciu, Monica
The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity
title The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity
title_full The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity
title_fullStr The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity
title_full_unstemmed The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity
title_short The Self-Pleasantness Judgment Modulates the Encoding Performance and the Default Mode Network Activity
title_sort self-pleasantness judgment modulates the encoding performance and the default mode network activity
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796013/
https://www.ncbi.nlm.nih.gov/pubmed/27047364
http://dx.doi.org/10.3389/fnhum.2016.00121
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