Cargando…

Development of a multicomponent vaccine for Streptococcus pyogenes based on the antigenic targets of IVIG

OBJECTIVES: Despite over a century of research and the careful scrutiny of many promising targets, there is currently no vaccine available for the prevention of Streptococcus pyogenes infection. Through analysis of the protective, anti-streptococcal components of pooled human immunoglobulin, we prev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reglinski, Mark, Lynskey, Nicola N., Choi, Yoon Jung, Edwards, Robert J., Sriskandan, Shiranee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	W.B. Saunders 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796040/ https://www.ncbi.nlm.nih.gov/pubmed/26880087 http://dx.doi.org/10.1016/j.jinf.2016.02.002

Ejemplares similares

Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin
por: Reglinski, Mark, et al.
Publicado: (2015)

Modification of the classical Lancefield assay of group A streptococcal killing to reduce inter-donor variation
por: Reglinski, Mark, et al.
Publicado: (2016)

Non-Invasive Monitoring of Streptococcus pyogenes Vaccine Efficacy Using Biophotonic Imaging
por: Alam, Faraz M., et al.
Publicado: (2013)

Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection
por: Siggins, Matthew K., et al.
Publicado: (2020)

Impact of immunization against SpyCEP during invasive disease with two streptococcal species: Streptococcus pyogenes and Streptococcus equi
por: Turner, Claire E., et al.
Publicado: (2009)

Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes
por: Edwards, Robert J., et al.
Publicado: (2018)

The contribution of group A streptococcal virulence determinants to the pathogenesis of sepsis
por: Reglinski, Mark, et al.
Publicado: (2014)

Treatment potential of pathogen-reactive antibodies sequentially purified from pooled human immunoglobulin
por: Reglinski, Mark, et al.
Publicado: (2019)

Structure–activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal
por: Pearson, Max, et al.
Publicado: (2023)

Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase
por: Lynskey, Nicola N., et al.
Publicado: (2017)

Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection
por: Alam, Faraz M., et al.
Publicado: (2013)

Molecular Analysis of an Outbreak of Lethal Postpartum Sepsis Caused by Streptococcus pyogenes
por: Turner, Claire E., et al.
Publicado: (2013)

Correction: Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection
por: Alam, Faraz M., et al.
Publicado: (2013)

Correlates of immunity to Group A Streptococcus: a pathway to vaccine development
por: Frost, Hannah, et al.
Publicado: (2023)

Safety of Streptococcus pyogenes Vaccines: Anticipating and Overcoming Challenges for Clinical Trials and Post-Marketing Monitoring
por: Asturias, Edwin J, et al.
Publicado: (2023)

The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression
por: Turner, Claire E., et al.
Publicado: (2019)

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study
por: Lynskey, Nicola N, et al.
Publicado: (2019)

Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction
por: Lynskey, Nicola N., et al.
Publicado: (2015)

Characterization of emergent toxigenic M1(UK) Streptococcus pyogenes and associated sublineages
por: Li, Ho Kwong, et al.
Publicado: (2023)

Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract
por: Kurupati, Prathiba, et al.
Publicado: (2010)

Invasive Disease and Toxic Shock due to Zoonotic Streptococcus suis: An Emerging Infection in the East?
por: Sriskandan, Shiranee, et al.
Publicado: (2006)

Turner et al. Reply to “Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions”
por: Turner, Claire E., et al.
Publicado: (2015)

RocA Truncation Underpins Hyper-Encapsulation, Carriage Longevity and Transmissibility of Serotype M18 Group A Streptococci
por: Lynskey, Nicola N., et al.
Publicado: (2013)

The Streptococcus pyogenes vaccine landscape
por: Walkinshaw, Donald R., et al.
Publicado: (2023)

Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation
por: Turner, Claire E., et al.
Publicado: (2012)

Familial Transmission of emm12 Group A Streptococcus
por: Mearkle, Rachel, et al.
Publicado: (2018)

Streptococcus pyogenes: Pathogenesis and the Current Status of Vaccines
por: Wang, Jiachao, et al.
Publicado: (2023)

Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes
por: McKenna, Sophie, et al.
Publicado: (2020)

Streptococcus pyogenes balanoposthitis
por: Norimatsu, Yuta, et al.
Publicado: (2020)

Identifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children
por: Mortensen, Rasmus, et al.
Publicado: (2016)

Frequency of transmission, asymptomatic shedding, and airborne spread of Streptococcus pyogenes in schoolchildren exposed to scarlet fever: a prospective, longitudinal, multicohort, molecular epidemiological, contact-tracing study in England, UK
por: Cordery, Rebecca, et al.
Publicado: (2022)

Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus
por: Smith, Debra S., et al.
Publicado: (2016)

Interactions of Lactobacilli with Pathogenic Streptococcus pyogenes
por: Westbroek, Mark L., et al.
Publicado: (2010)

Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease
por: Tan, Lionel K. K., et al.
Publicado: (2021)

CRISPR-Cas in Streptococcus pyogenes
por: Le Rhun, Anaïs, et al.
Publicado: (2019)

Multicomponent Vaccines against Group A Streptococcus Can Effectively Target Broad Disease Presentations
por: Shaw, Helen A., et al.
Publicado: (2021)

Streptococcus Pneumoniae-Related Hemophagocytic Lymphohistiocytosis Treated with Intravenous Immunoglobulin (IVIG) and Steroids
por: Dumancas, Carissa Y., et al.
Publicado: (2018)

Tregitopes and impaired antigen presentation: Drivers of the immunomodulatory effects of IVIg?
por: Sordé, Laetitia, et al.
Publicado: (2017)

THE SERUM OPACITY REACTION OF STREPTOCOCCUS PYOGENES : THE DEMONSTRATION OF MULTIPLE, STRAIN-SPECIFIC LIPOPROTEINASE ANTIGENS
por: Top, Franklin H., et al.
Publicado: (1968)

Overexpression and Enzymatic Assessment of Antigenic Fragments of Hyaluronidase Recombinant Protein From Streptococcus pyogenes
por: Sadoogh Abbasian, Shabnam, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ivtc23ipnknba1l1ll1gv066lc