Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice

Immune tolerance is executed partly by Foxp3(+)regulatory T (Treg) cells, which suppress autoreactive T cells. In autoimmune type 1 diabetes (T1D) impaired tolerance promotes destruction of insulin-producing β-cells. The development of autoantigen-specific vaccination strategies for Foxp3(+)Treg-ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Serr, Isabelle, Fürst, Rainer W., Achenbach, Peter, Scherm, Martin G., Gökmen, Füsun, Haupt, Florian, Sedlmeier, Eva-Maria, Knopff, Annette, Shultz, Leonard, Willis, Richard A., Ziegler, Anette-Gabriele, Daniel, Carolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796321/
https://www.ncbi.nlm.nih.gov/pubmed/26975663
http://dx.doi.org/10.1038/ncomms10991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796321/
https://www.ncbi.nlm.nih.gov/pubmed/26975663
http://dx.doi.org/10.1038/ncomms10991

Ejemplares similares