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Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice

Immune tolerance is executed partly by Foxp3(+)regulatory T (Treg) cells, which suppress autoreactive T cells. In autoimmune type 1 diabetes (T1D) impaired tolerance promotes destruction of insulin-producing β-cells. The development of autoantigen-specific vaccination strategies for Foxp3(+)Treg-ind...

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Detalles Bibliográficos
Autores principales:	Serr, Isabelle, Fürst, Rainer W., Achenbach, Peter, Scherm, Martin G., Gökmen, Füsun, Haupt, Florian, Sedlmeier, Eva-Maria, Knopff, Annette, Shultz, Leonard, Willis, Richard A., Ziegler, Anette-Gabriele, Daniel, Carolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796321/ https://www.ncbi.nlm.nih.gov/pubmed/26975663 http://dx.doi.org/10.1038/ncomms10991

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