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Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome

To evaluate the relevance of body mass index (BMI), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH ratio with clinical symptoms in polycystic ovary syndrome (PCOS) women. METHODS: We reviewed the medical records of all women visited in the PCOS Clinic of Babol (Iran) from 20...

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Autores principales: Esmaeilzadeh, Seddigheh, Andarieh, Maryam Ghanbari, Ghadimi, Reza, Delavar, Mouloud Agajani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Canadian Center of Science and Education 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796454/
https://www.ncbi.nlm.nih.gov/pubmed/25716399
http://dx.doi.org/10.5539/gjhs.v7n2p101
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author Esmaeilzadeh, Seddigheh
Andarieh, Maryam Ghanbari
Ghadimi, Reza
Delavar, Mouloud Agajani
author_facet Esmaeilzadeh, Seddigheh
Andarieh, Maryam Ghanbari
Ghadimi, Reza
Delavar, Mouloud Agajani
author_sort Esmaeilzadeh, Seddigheh
collection PubMed
description To evaluate the relevance of body mass index (BMI), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH ratio with clinical symptoms in polycystic ovary syndrome (PCOS) women. METHODS: We reviewed the medical records of all women visited in the PCOS Clinic of Babol (Iran) from 2008 to 2012. A retrospective cross-sectional study was conducted on 175 PCOS women; aged 18–38 years diagnosed based on the Rotterdam criteria. Among the PCOs women, the prevalence of oligomenorrhea, acne, and hirsutism were found to be 92.0%, 31.4%, and 78.9%, respectively. Positive finding of polycystic ovaries was observed in 89.1% of PCOS women with by using sonography. A total of 69.2% overweight/obesity patients had polycystic ovary morphology on ultrasound image. Compared with non- overweight/obesity, the adjusted OR of PCOS women for sonographic view of polycystic ovaries was 4.33 (95% CI, 1.42-13.15, p=0.001), Nevertheless, the adjusted odds ratio (OR) showed no significant associations between LH, FSH, and LH/FSH ratio with clinical symptoms in these women. The findings of this study indicated that the overweight/obese women with PCOS are at an increased risk for sonographic view of polycystic ovaries. Therefore, it is suggested that successful weight loss is the most effective method of restoring ovulation, menstruation that should be used as major advice in obese PCOS patients.
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spelling pubmed-47964542016-04-21 Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome Esmaeilzadeh, Seddigheh Andarieh, Maryam Ghanbari Ghadimi, Reza Delavar, Mouloud Agajani Glob J Health Sci Articles To evaluate the relevance of body mass index (BMI), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH ratio with clinical symptoms in polycystic ovary syndrome (PCOS) women. METHODS: We reviewed the medical records of all women visited in the PCOS Clinic of Babol (Iran) from 2008 to 2012. A retrospective cross-sectional study was conducted on 175 PCOS women; aged 18–38 years diagnosed based on the Rotterdam criteria. Among the PCOs women, the prevalence of oligomenorrhea, acne, and hirsutism were found to be 92.0%, 31.4%, and 78.9%, respectively. Positive finding of polycystic ovaries was observed in 89.1% of PCOS women with by using sonography. A total of 69.2% overweight/obesity patients had polycystic ovary morphology on ultrasound image. Compared with non- overweight/obesity, the adjusted OR of PCOS women for sonographic view of polycystic ovaries was 4.33 (95% CI, 1.42-13.15, p=0.001), Nevertheless, the adjusted odds ratio (OR) showed no significant associations between LH, FSH, and LH/FSH ratio with clinical symptoms in these women. The findings of this study indicated that the overweight/obese women with PCOS are at an increased risk for sonographic view of polycystic ovaries. Therefore, it is suggested that successful weight loss is the most effective method of restoring ovulation, menstruation that should be used as major advice in obese PCOS patients. Canadian Center of Science and Education 2015-03 2014-09-28 /pmc/articles/PMC4796454/ /pubmed/25716399 http://dx.doi.org/10.5539/gjhs.v7n2p101 Text en Copyright: © Canadian Center of Science and Education http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Articles
Esmaeilzadeh, Seddigheh
Andarieh, Maryam Ghanbari
Ghadimi, Reza
Delavar, Mouloud Agajani
Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome
title Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome
title_full Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome
title_fullStr Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome
title_full_unstemmed Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome
title_short Body Mass Index and Gonadotropin Hormones (LH & FSH) Associate With Clinical Symptoms Among Women With Polycystic Ovary Syndrome
title_sort body mass index and gonadotropin hormones (lh & fsh) associate with clinical symptoms among women with polycystic ovary syndrome
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796454/
https://www.ncbi.nlm.nih.gov/pubmed/25716399
http://dx.doi.org/10.5539/gjhs.v7n2p101
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