Calcineurin B stimulates cytokine production through a CD14-independent Toll-like receptor 4 pathway

The calcineurin B subunit (CnB) is the regulatory subunit of Cn, a Ca(2+)/calmodulin-dependent serine/threonine protein phosphatase. In this study, we demonstrate that extracellular CnB was effectively internalized through a CD14-independent Toll-like receptor 4 (TLR4) pathway, which led to the phos...

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Detalles Bibliográficos
Autores principales: Wu, Wu, Chen, Qing, Geng, Feng, Tong, Li, Yang, Rui, Yang, Jinju, Zhang, Hongwei, Jia, Zongchao, Wei, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796594/
https://www.ncbi.nlm.nih.gov/pubmed/26471241
http://dx.doi.org/10.1038/icb.2015.91

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