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Altered Na/Ca exchange distribution in ventricular myocytes from failing hearts

In mammalian cardiac ventricular myocytes, Ca efflux via Na/Ca exchange (NCX) occurs predominantly at T tubules. Heart failure is associated with disrupted t-tubular structure, but its effect on t-tubular function is less clear. We therefore investigated t-tubular NCX activity in ventricular myocyte...

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Detalles Bibliográficos
Autores principales:	Gadeberg, Hanne C., Bryant, Simon M., James, Andrew F., Orchard, Clive H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2015
Materias:	Cardiac Excitation and Contraction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796630/ https://www.ncbi.nlm.nih.gov/pubmed/26566728 http://dx.doi.org/10.1152/ajpheart.00597.2015

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