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Current strategies against invasive fungal infections in patients with aplastic anemia, strong power and weak weapon, a case report and review of literature

We report an 18 year old boy with Aplastic anemia complicated by serious fungal rhinosinusitis. Despite prompt treatment and early repeated surgical debridements, he died after about more than 6 weeks of hard challenges with fungal infections. Current strategies against invasive fungal infections (I...

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Detalles Bibliográficos
Autores principales: Zekavat, Omid Reza, Amanati, Ali, Saleh, Fazl, Abdolkarimi, Babak, Fathpour, Gholamreza, Badiee, Parisa, Geramizadeh, Bita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796718/
https://www.ncbi.nlm.nih.gov/pubmed/27047751
http://dx.doi.org/10.1016/j.mmcr.2016.03.003
Descripción
Sumario:We report an 18 year old boy with Aplastic anemia complicated by serious fungal rhinosinusitis. Despite prompt treatment and early repeated surgical debridements, he died after about more than 6 weeks of hard challenges with fungal infections. Current strategies against invasive fungal infections (IFIs) in patients with Aplastic anemia may be inadequate for the management of serious complications. Antifungal prophylaxis is highly recommended in pre-transplant period for severe form of Aplastic anemia.