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Substrate engagement of integrins α(5)β(1) and α(v)β(3) is necessary, but not sufficient, for high directional persistence in migration on fibronectin
The interplay between specific integrin-mediated matrix adhesion and directional persistence in cell migration is not well understood. Here, we characterized fibroblast adhesion and migration on the extracellular matrix glycoproteins fibronectin and vitronectin, focusing on the role of α(5)β(1) and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796868/ https://www.ncbi.nlm.nih.gov/pubmed/26987342 http://dx.doi.org/10.1038/srep23258 |