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Sox2 in the differentiation of cochlear progenitor cells

HMG domain transcription factor, Sox2, is a critical gene for the development of cochlear hair cells, the receptor cells for hearing, but this has been ascribed to expansion of the progenitors that become hair cells. Here, we show that Sox2 activated Atoh1, a transcription factor important for hair...

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Detalles Bibliográficos
Autores principales: Kempfle, Judith S., Turban, Jack L., Edge, Albert S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796895/
https://www.ncbi.nlm.nih.gov/pubmed/26988140
http://dx.doi.org/10.1038/srep23293

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