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Bottom-up GGM algorithm for constructing multilayered hierarchical gene regulatory networks that govern biological pathways or processes

BACKGROUND: Multilayered hierarchical gene regulatory networks (ML-hGRNs) are very important for understanding genetics regulation of biological pathways. However, there are currently no computational algorithms available for directly building ML-hGRNs that regulate biological pathways. RESULTS: A b...

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Detalles Bibliográficos
Autores principales: Kumari, Sapna, Deng, Wenping, Gunasekara, Chathura, Chiang, Vincent, Chen, Huann-sheng, Ma, Hao, Davis, Xin, Wei, Hairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797117/
https://www.ncbi.nlm.nih.gov/pubmed/26993098
http://dx.doi.org/10.1186/s12859-016-0981-1