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A Modified Coupled Spectrophotometric Method to Detect 2-5 Oligoadenylate Synthetase Activity in Prostate Cell Lines

BACKGROUND: 2’-5’ oligoadenylate synthetases (OAS) are interferon inducible enzymes that polymerizes ATP to 2’-5’-linked oligomers of adenylate (2-5As). As part of the innate immune response, these enzymes are activated by viral double stranded RNA or mRNAs with significant double stranded structure...

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Detalles Bibliográficos
Autores principales: Bhosle, Sushma M., Hunt, Aisha, Chaudhary, Jaideep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797170/
https://www.ncbi.nlm.nih.gov/pubmed/26997919
http://dx.doi.org/10.1186/s12575-016-0038-x