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Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging

BACKGROUND: Surfactant protein A (SP-A) contributes to lung immunity by regulating inflammation and responses to microorganisms invading the lung. The huge genetic variability of SP-A in humans implies that this protein is highly important in tightly regulating the lung immune response. Proteomic st...

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Detalles Bibliográficos
Autores principales:	Tsotakos, Nikolaos, Phelps, David S., Yengo, Christopher M., Chinchilli, Vernon M., Floros, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797174/ https://www.ncbi.nlm.nih.gov/pubmed/26998217 http://dx.doi.org/10.1186/s13293-016-0071-0

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