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Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) has been associated with the acquisition of metastatic potential and the resistance of cancer cells to therapeutic treatments. MCF-7 breast cancer cells engineered to constitutively express the zinc-finger transcriptional repressor gene Snail (M...

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Detalles Bibliográficos
Autores principales:	Mezencev, Roman, Matyunina, Lilya V., Jabbari, Neda, McDonald, John F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797178/ https://www.ncbi.nlm.nih.gov/pubmed/26988558 http://dx.doi.org/10.1186/s12885-016-2274-5

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