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CDK4 and miR-15a comprise an abnormal automodulatory feedback loop stimulating the pathogenesis and inducing chemotherapy resistance in nasopharyngeal carcinoma

BACKGROUND: In previous investigation, we reported that stably knocking down cyclin-dependent kinase 4(CDK4) induced expression of let-7c, which further suppressed cell cycle transition and cell growth by modulating cell cycle signaling in nasopharyngeal carcinoma (NPC). In this study, we further ex...

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Detalles Bibliográficos
Autores principales:	Liu, Zhen, Cheng, Chao, Luo, Xiaojun, Xia, Qiong, Zhang, Yejie, Long, Xiaobing, Jiang, Qingping, Fang, Weiyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797221/ https://www.ncbi.nlm.nih.gov/pubmed/26993269 http://dx.doi.org/10.1186/s12885-016-2277-2

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