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Sample size calculations in clinical research should also be based on ethical principles
Sample size calculations based on too narrow a width, or with lower and upper confidence limits bounded by fixed cut-off points, not only increase power-based sample sizes to ethically unacceptable levels (thus making research practically unfeasible) but also greatly increase the costs and burdens o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797226/ https://www.ncbi.nlm.nih.gov/pubmed/26993625 http://dx.doi.org/10.1186/s13063-016-1277-5 |