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Simultaneous characterization of sense and antisense genomic processes by the double-stranded hidden Markov model
Hidden Markov models (HMMs) have been extensively used to dissect the genome into functionally distinct regions using data such as RNA expression or DNA binding measurements. It is a challenge to disentangle processes occurring on complementary strands of the same genomic region. We present the doub...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797261/ https://www.ncbi.nlm.nih.gov/pubmed/26578558 http://dx.doi.org/10.1093/nar/gkv1184 |