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Simultaneous characterization of sense and antisense genomic processes by the double-stranded hidden Markov model

Hidden Markov models (HMMs) have been extensively used to dissect the genome into functionally distinct regions using data such as RNA expression or DNA binding measurements. It is a challenge to disentangle processes occurring on complementary strands of the same genomic region. We present the doub...

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Detalles Bibliográficos
Autores principales: Glas, Julia, Dümcke, Sebastian, Zacher, Benedikt, Poron, Don, Gagneur, Julien, Tresch, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797261/
https://www.ncbi.nlm.nih.gov/pubmed/26578558
http://dx.doi.org/10.1093/nar/gkv1184

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