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Structure of the mammalian antimicrobial peptide Bac7(1–16) bound within the exit tunnel of a bacterial ribosome

Proline-rich antimicrobial peptides (PrAMPs) produced as part of the innate immune response of animals, insects and plants represent a vast, untapped resource for the treatment of multidrug-resistant bacterial infections. PrAMPs such as oncocin or bactenecin-7 (Bac7) interact with the bacterial ribo...

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Detalles Bibliográficos
Autores principales: Seefeldt, A. Carolin, Graf, Michael, Pérébaskine, Natacha, Nguyen, Fabian, Arenz, Stefan, Mardirossian, Mario, Scocchi, Marco, Wilson, Daniel N., Innis, C. Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797285/
https://www.ncbi.nlm.nih.gov/pubmed/26792896
http://dx.doi.org/10.1093/nar/gkv1545