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Molecular basis for DNA strand displacement by NHEJ repair polymerases

The non-homologous end-joining (NHEJ) pathway repairs DNA double-strand breaks (DSBs) in all domains of life. Archaea and bacteria utilize a conserved set of multifunctional proteins in a pathway termed Archaeo-Prokaryotic (AP) NHEJ that facilitates DSB repair. Archaeal NHEJ polymerases (Pol) are ca...

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Detalles Bibliográficos
Autores principales:	Bartlett, Edward J., Brissett, Nigel C., Plocinski, Przemyslaw, Carlberg, Tom, Doherty, Aidan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797286/ https://www.ncbi.nlm.nih.gov/pubmed/26405198 http://dx.doi.org/10.1093/nar/gkv965

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