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A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs

The export of messenger RNAs (mRNAs) is the final of several nuclear posttranscriptional steps of gene expression. The formation of export-competent mRNPs involves the recruitment of export factors that are assumed to facilitate transport of the mature mRNAs. Using in vitro splicing assays, we show...

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Detalles Bibliográficos
Autores principales: Gromadzka, Agnieszka M., Steckelberg, Anna-Lena, Singh, Kusum K., Hofmann, Kay, Gehring, Niels H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797287/
https://www.ncbi.nlm.nih.gov/pubmed/26773052
http://dx.doi.org/10.1093/nar/gkw009