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Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition
With bacterial resistance becoming a serious threat to global public health, antimicrobial peptides (AMPs) have become a promising area of focus in antibiotic research. AMPs are derived from a diverse range of species, from prokaryotes to humans, with a mechanism of action that often involves disrup...
Autores principales: | Gagnon, Matthieu G., Roy, Raktim N., Lomakin, Ivan B., Florin, Tanja, Mankin, Alexander S., Steitz, Thomas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797290/ https://www.ncbi.nlm.nih.gov/pubmed/26809677 http://dx.doi.org/10.1093/nar/gkw018 |
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