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Discovering hotspots in functional genomic data superposed on 3D chromatin configuration reconstructions

The spatial organization of the genome influences cellular function, notably gene regulation. Recent studies have assessed the three-dimensional (3D) co-localization of functional annotations (e.g. centromeres, long terminal repeats) using 3D genome reconstructions from Hi-C (genome-wide chromosome...

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Detalles Bibliográficos
Autores principales: Capurso, Daniel, Bengtsson, Henrik, Segal, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797302/
https://www.ncbi.nlm.nih.gov/pubmed/26869583
http://dx.doi.org/10.1093/nar/gkw070