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Discovering hotspots in functional genomic data superposed on 3D chromatin configuration reconstructions
The spatial organization of the genome influences cellular function, notably gene regulation. Recent studies have assessed the three-dimensional (3D) co-localization of functional annotations (e.g. centromeres, long terminal repeats) using 3D genome reconstructions from Hi-C (genome-wide chromosome...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797302/ https://www.ncbi.nlm.nih.gov/pubmed/26869583 http://dx.doi.org/10.1093/nar/gkw070 |