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Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency
T lymphocytes are essential mediators of immunity that are produced by the thymus in proportion to its size. The thymus atrophies rapidly with age, resulting in progressive diminution of new T cell production. This decreased output is compensated by duplication of existing T cells, but it results in...
Autores principales: | Griffith, Ann V, Venables, Thomas, Shi, Jianjun, Farr, Andrew, van Remmen, Holly, Szweda, Luke, Fallahi, Mohammad, Rabinovitch, Peter, Petrie, Howard T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797338/ https://www.ncbi.nlm.nih.gov/pubmed/26257169 http://dx.doi.org/10.1016/j.celrep.2015.07.008 |
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