Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents

A stereoselective hypervalent iodine‐promoted oxidative rearrangement of 1,1‐disubstituted alkenes has been developed. This practically simple protocol provides access to enantioenriched α‐arylated ketones without the use of transition metals from readily accessible alkenes.

Detalles Bibliográficos
Autores principales: Brown, Michael, Kumar, Ravi, Rehbein, Julia, Wirth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797713/
https://www.ncbi.nlm.nih.gov/pubmed/26800241
http://dx.doi.org/10.1002/chem.201504844
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author Brown, Michael
Kumar, Ravi
Rehbein, Julia
Wirth, Thomas
author_facet Brown, Michael
Kumar, Ravi
Rehbein, Julia
Wirth, Thomas
author_sort Brown, Michael
collection PubMed
description A stereoselective hypervalent iodine‐promoted oxidative rearrangement of 1,1‐disubstituted alkenes has been developed. This practically simple protocol provides access to enantioenriched α‐arylated ketones without the use of transition metals from readily accessible alkenes.
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spelling pubmed-47977132016-03-21 Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents Brown, Michael Kumar, Ravi Rehbein, Julia Wirth, Thomas Chemistry Full Papers A stereoselective hypervalent iodine‐promoted oxidative rearrangement of 1,1‐disubstituted alkenes has been developed. This practically simple protocol provides access to enantioenriched α‐arylated ketones without the use of transition metals from readily accessible alkenes. John Wiley and Sons Inc. 2016-01-21 2016-03-14 /pmc/articles/PMC4797713/ /pubmed/26800241 http://dx.doi.org/10.1002/chem.201504844 Text en © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Papers
Brown, Michael
Kumar, Ravi
Rehbein, Julia
Wirth, Thomas
Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
title Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
title_full Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
title_fullStr Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
title_full_unstemmed Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
title_short Enantioselective Oxidative Rearrangements with Chiral Hypervalent Iodine Reagents
title_sort enantioselective oxidative rearrangements with chiral hypervalent iodine reagents
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797713/
https://www.ncbi.nlm.nih.gov/pubmed/26800241
http://dx.doi.org/10.1002/chem.201504844
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AT rehbeinjulia enantioselectiveoxidativerearrangementswithchiralhypervalentiodinereagents
AT wirththomas enantioselectiveoxidativerearrangementswithchiralhypervalentiodinereagents

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