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The metabolic phenotype of rodent sepsis: cause for concern?
PURPOSE: Rodent models of sepsis are frequently used to investigate pathophysiological mechanisms and to evaluate putative therapeutic strategies. However, preclinical efficacy in these models has failed to translate to the clinical setting. We thus questioned the representativeness of such models a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797805/ https://www.ncbi.nlm.nih.gov/pubmed/26266794 http://dx.doi.org/10.1186/2197-425X-1-6 |