Cargando…
Amyloid-beta Alzheimer targets — protein processing, lipid rafts, and amyloid-beta pores
Amyloid beta (Aβ), the hallmark of Alzheimer’s Disease (AD), now appears to be deleterious in its low number aggregate form as opposed to the macroscopic Aβ fibers historically seen postmortem. While Alzheimer targets, such as the tau protein, amyloid precursor protein (APP) processing, and immune s...
Autores principales: | Arbor, Sage C., LaFontaine, Mike, Cumbay, Medhane |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
YJBM
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797837/ https://www.ncbi.nlm.nih.gov/pubmed/27505013 |
Ejemplares similares
-
Targeting amyloid precursor protein shuttling and processing - long before amyloid beta formation
por: Arbor, Sage
Publicado: (2017) -
Mechanisms of Amyloid-Beta Peptide Uptake by Neurons: The Role of Lipid Rafts and Lipid Raft-Associated Proteins
por: Lai, Aaron Y., et al.
Publicado: (2010) -
Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease
por: Zhou, Xin, et al.
Publicado: (2014) -
Amyloid Beta Is Internalized via Macropinocytosis, an HSPG- and Lipid Raft-Dependent and Rac1-Mediated Process
por: Nazere, Keyoumu, et al.
Publicado: (2022) -
Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
por: Ehehalt, Robert, et al.
Publicado: (2003)